Controls & Reference Materials
Seraseq® NGS Reference Materials
SHOP PRODUCTSSeraCare’s comprehensive suite of patient-like reference materials accelerates development, streamlines validation, and ensures confidence in results of today’s demanding clinical genomics assays. Our platform agnostic, ground-truth reference materials can be used through all development phases to verify actionable and challenging variants as well as complex genomic signatures in patient samples.
Compatible Workflows
- Next Generation Sequencing
- Sanger Sequencing
- Real-time PCR and digital PCR (dPCR)
- Microarray
A wide range of clinical applications
- Somatic cancer - solid tumor, heme malignancy, immuno-oncology, and liquid biopsy
- Reproductive health - NIPT (trisomies, microdeletion, sex chromosome aneuploidies)
- Inherited cancer and cariomyopathy
- Infectious disease - HIV and SARS-CoV-2
Key Features
- Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, and RNA fusions
- Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs
- Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA in plasma, and FFPE
- Manufactured in cGMP-compliant, ISO 13485-certified facilities
- Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers
Develop and validate assays faster
- Establish assay accuracy, precision, reproducibility, sensitivity, and LoD with confidence
- Expedite assay design to analytical validation turnaround time without sacrificing quality
Launch on time and on budget
- Regulatory-compliant reference materials for analytical validation accepted by the New York State Department of Health, the FDA, and other regulatory bodies
Ensure confidence in your results
- Confirm detection of common, rare, and technically challenging variants at expected allele frequencies in patient samples
- Validate measurement and reporting of complex genomic signatures and chromosomal aneuploidies
- Ensure consistent run-after-run assay performance
Custom Solution Capabilities
- Expert-designed bespoke reference materials configured to meet your specific assay requirements
- A high degree of flexibility – customized allele frequency, format, variant type, and matrix
- Choose from a library of >400 clinically actionable variants or design your own
- Fast project turnaround time with full traceability from sourcing through processing and delivery
- Deep technical, quality management, and regulatory expertise to consult on projects
For research use only. Not for use in diagnostic procedures.
